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Molecular Determinants for OMF Selectivity in Tripartite RND Multidrug Efflux Systems

Tripartite multidrug RND efflux systems made of an inner membrane transporter, an outer membrane factor (OMF) and a periplasmic adaptor protein (PAP) form a canal to expel drugs across Gram-negative cell wall. Structures of MexA–MexB–OprM and AcrA–AcrB–TolC, from Pseudomonas aeruginosa and Escherich...

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Detalles Bibliográficos
Autores principales: Boyer, Esther, Dessolin, Jean, Lustig, Margaux, Decossas, Marion, Phan, Gilles, Cece, Quentin, Durand, Grégory, Dubois, Véronique, Sansen, Joris, Taveau, Jean-Christophe, Broutin, Isabelle, Daury, Laetitia, Lambert, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868134/
https://www.ncbi.nlm.nih.gov/pubmed/35203729
http://dx.doi.org/10.3390/antibiotics11020126