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A Journey into the Clinical Relevance of Heme Oxygenase 1 for Human Inflammatory Disease and Viral Clearance: Why Does It Matter on the COVID-19 Scene?

Heme oxygenase 1 (HO-1), the rate-limiting enzyme in heme degradation, is involved in the maintenance of cellular homeostasis, exerting a cytoprotective role by its antioxidative and anti-inflammatory functions. HO-1 and its end products, biliverdin, carbon monoxide and free iron (Fe(2+)), confer cy...

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Detalles Bibliográficos
Autores principales: Toro, Ayelen, Ruiz, María Sol, Lage-Vickers, Sofia, Sanchis, Pablo, Sabater, Agustina, Pascual, Gaston, Seniuk, Rocio, Cascardo, Florencia, Ledesma-Bazan, Sabrina, Vilicich, Felipe, Vazquez, Elba, Gueron, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868141/
https://www.ncbi.nlm.nih.gov/pubmed/35204159
http://dx.doi.org/10.3390/antiox11020276