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Na(+)/K(+)-ATPase Alpha 2 Isoform Elicits Rac1-Dependent Oxidative Stress and TLR4-Induced Inflammation in the Hypothalamic Paraventricular Nucleus in High Salt-Induced Hypertension

Numerous studies have indicated that a high salt diet inhibits brain Na(+)/K(+)-ATPase (NKA) activity, and affects oxidative stress and inflammation in the paraventricular nucleus (PVN). Furthermore, Na(+)/K(+)-ATPase alpha 2-isoform (NKA α2) may be a target in the brain, taking part in the developm...

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Detalles Bibliográficos
Autores principales: Su, Qing, Yu, Xiao-Jing, Wang, Xiao-Min, Peng, Bo, Bai, Juan, Li, Hong-Bao, Li, Ying, Xia, Wen-Jie, Fu, Li-Yan, Liu, Kai-Li, Liu, Jin-Jun, Kang, Yu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868219/
https://www.ncbi.nlm.nih.gov/pubmed/35204171
http://dx.doi.org/10.3390/antiox11020288