Role of Lung P450 Oxidoreductase in Paraquat-Induced Collagen Deposition in the Lung

Paraquat (PQ) is an agrochemical known to cause pulmonary fibrosis. PQ-induced collagen deposition in the lung is thought to require enzymatic formation of PQ radicals, but the specific enzymes responsible for this bioactivation event in vivo have not been identified. We tested the hypothesis that l...

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Detalles Bibliográficos
Autores principales: Kovalchuk, Nataliia, Jilek, Joseph L., Van Winkle, Laura S., Cherrington, Nathan J., Ding, Xinxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868258/
https://www.ncbi.nlm.nih.gov/pubmed/35204102
http://dx.doi.org/10.3390/antiox11020219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868258/
https://www.ncbi.nlm.nih.gov/pubmed/35204102
http://dx.doi.org/10.3390/antiox11020219

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