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Role of Lung P450 Oxidoreductase in Paraquat-Induced Collagen Deposition in the Lung
Paraquat (PQ) is an agrochemical known to cause pulmonary fibrosis. PQ-induced collagen deposition in the lung is thought to require enzymatic formation of PQ radicals, but the specific enzymes responsible for this bioactivation event in vivo have not been identified. We tested the hypothesis that l...
Autores principales: | Kovalchuk, Nataliia, Jilek, Joseph L., Van Winkle, Laura S., Cherrington, Nathan J., Ding, Xinxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868258/ https://www.ncbi.nlm.nih.gov/pubmed/35204102 http://dx.doi.org/10.3390/antiox11020219 |
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