Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the Substantia Nigra of Male Rodents and Primary Mesencephalic Cultures

The tissue renin–angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson’s disease (PD). We studied the activation of the NLRP3 inflammasome in the substantia nigra...

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Detalles Bibliográficos
Autores principales: Quijano, Aloia, Diaz-Ruiz, Carmen, Lopez-Lopez, Andrea, Villar-Cheda, Begoña, Muñoz, Ana, Rodriguez-Perez, Ana I., Labandeira-Garcia, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868290/
https://www.ncbi.nlm.nih.gov/pubmed/35204211
http://dx.doi.org/10.3390/antiox11020329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868290/
https://www.ncbi.nlm.nih.gov/pubmed/35204211
http://dx.doi.org/10.3390/antiox11020329

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