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LC-HRMS-Based Identification of Transformation Products of the Drug Salinomycin Generated by Electrochemistry and Liver Microsome

The drug salinomycin (SAL) is a polyether antibiotic and used in veterinary medicine as coccidiostat and growth promoter. Recently, SAL was suggested as a potential anticancer drug. However, transformation products (TPs) resulting from metabolic and environmental degradation of SAL are incompletely...

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Detalles Bibliográficos
Autores principales: Knoche, Lisa, Lisec, Jan, Schwerdtle, Tanja, Koch, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868298/
https://www.ncbi.nlm.nih.gov/pubmed/35203758
http://dx.doi.org/10.3390/antibiotics11020155