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LC-HRMS-Based Identification of Transformation Products of the Drug Salinomycin Generated by Electrochemistry and Liver Microsome
The drug salinomycin (SAL) is a polyether antibiotic and used in veterinary medicine as coccidiostat and growth promoter. Recently, SAL was suggested as a potential anticancer drug. However, transformation products (TPs) resulting from metabolic and environmental degradation of SAL are incompletely...
Autores principales: | Knoche, Lisa, Lisec, Jan, Schwerdtle, Tanja, Koch, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868298/ https://www.ncbi.nlm.nih.gov/pubmed/35203758 http://dx.doi.org/10.3390/antibiotics11020155 |
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