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Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial

Centella asiatica is reputed in Eastern medicine to improve cognitive function in humans. Preclinical studies have demonstrated that aqueous extracts of C. asiatica improve cognition in mouse models of aging and Alzheimer’s disease (AD) through the modulation of mitochondrial biogenesis and nuclear...

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Detalles Bibliográficos
Autores principales: Wright, Kirsten M., Bollen, Melissa, David, Jason, Speers, Alex B., Brandes, Mikah S., Gray, Nora E., Alcázar Magaña, Armando, McClure, Christine, Stevens, Jan F., Maier, Claudia S., Quinn, Joseph F., Soumyanath, Amala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868383/
https://www.ncbi.nlm.nih.gov/pubmed/35204098
http://dx.doi.org/10.3390/antiox11020215