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Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial
Centella asiatica is reputed in Eastern medicine to improve cognitive function in humans. Preclinical studies have demonstrated that aqueous extracts of C. asiatica improve cognition in mouse models of aging and Alzheimer’s disease (AD) through the modulation of mitochondrial biogenesis and nuclear...
Autores principales: | Wright, Kirsten M., Bollen, Melissa, David, Jason, Speers, Alex B., Brandes, Mikah S., Gray, Nora E., Alcázar Magaña, Armando, McClure, Christine, Stevens, Jan F., Maier, Claudia S., Quinn, Joseph F., Soumyanath, Amala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868383/ https://www.ncbi.nlm.nih.gov/pubmed/35204098 http://dx.doi.org/10.3390/antiox11020215 |
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