NRF2-Dependent Placental Effects Vary by Sex and Dose following Gestational Exposure to Ultrafine Particles

Exposure to ultrafine particles (UFPs, PM(0.1)) during pregnancy triggers placental oxidative stress and inflammation, similar to fine PM (PM(2.5)). The Nrf2 gene encodes a redox-sensitive transcription factor that is a major regulator of antioxidant and anti-inflammatory responses. Disruption of NR...

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Detalles Bibliográficos
Autores principales: Behlen, Jonathan C., Lau, Carmen H., Pendleton, Drew, Li, Yixin, Hoffmann, Aline Rodrigues, Golding, Michael C., Zhang, Renyi, Johnson, Natalie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868520/
https://www.ncbi.nlm.nih.gov/pubmed/35204234
http://dx.doi.org/10.3390/antiox11020352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868520/
https://www.ncbi.nlm.nih.gov/pubmed/35204234
http://dx.doi.org/10.3390/antiox11020352

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