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Influence of Glucose on Candida albicans and the Relevance of the Complement FH-Binding Molecule Hgt1 in a Murine Model of Candidiasis

Candidiasis is common in diabetic patients. Complement evasion is facilitated by binding complement factor H (FH). Since the expression of high-affinity glucose transporter 1 (Hgt1), a FH-binding molecule, is glucose-dependent, we aimed to study its relevance to the pathogenesis of Candida albicans....

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Detalles Bibliográficos
Autores principales: Harpf, Verena, Kenno, Samyr, Rambach, Günter, Fleischer, Verena, Parth, Nadia, Weichenberger, Christian X., Garred, Peter, Huber, Silke, Lass-Flörl, Cornelia, Speth, Cornelia, Würzner, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868559/
https://www.ncbi.nlm.nih.gov/pubmed/35203859
http://dx.doi.org/10.3390/antibiotics11020257