Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice

Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor used for the treatment of diabetes. This study examines the effects of dapagliflozin on human islets, focusing on alpha and beta cell composition in relation to function in vivo, following treatment of xeno-transplanted diabetic mi...

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Detalles Bibliográficos
Autores principales: Karlsson, Daniel, Ahnmark, Andrea, Sabirsh, Alan, Andréasson, Anne-Christine, Gennemark, Peter, Sandinge, Ann-Sofie, Chen, Lihua, Tyrberg, Björn, Lindén, Daniel, Sörhede Winzell, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868601/
https://www.ncbi.nlm.nih.gov/pubmed/35203411
http://dx.doi.org/10.3390/biomedicines10020203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868601/
https://www.ncbi.nlm.nih.gov/pubmed/35203411
http://dx.doi.org/10.3390/biomedicines10020203

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