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A De Novo Optimized Cell-Free System for the Expression of Soluble and Active Human Tumor Necrosis Factor-Alpha

SIMPLE SUMMARY: As a result of increasing demand for the pleiotropic cytokine TNF-α, recombinant human TNF-α protein with appropriate bioactivities was produced in several heterologous in vivo expression systems. While in vivo expression of this cytokine is laborious and lengthy, cell-free or in vit...

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Detalles Bibliográficos
Autores principales: El-Baky, Nawal Abd, EL-Fakharany, Esmail M., Sabry, Soraya A., El-Helow, Ehab R., Redwan, Elrashdy Mustafa, Sabry, Amira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868817/
https://www.ncbi.nlm.nih.gov/pubmed/35205024
http://dx.doi.org/10.3390/biology11020157