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Lysophosphatidic Acid Receptor 3 Promotes Mitochondrial Homeostasis against Oxidative Stress: Potential Therapeutic Approaches for Hutchinson–Gilford Progeria Syndrome

Lysophosphatidic acid (LPA) is a growth factor-like lipid mediator that regulates various physiological functions via activation of multiple LPA G protein-coupled receptors. We previously reported that LPA suppresses oxidative stress in premature aging Hutchinson-Gilford progeria syndrome (HGPS) pat...

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Detalles Bibliográficos
Autores principales: Chiang, Jui-Chung, Chen, Wei-Min, Newman, Ciara, Chen, Benjamin P. C., Lee, Hsinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869156/
https://www.ncbi.nlm.nih.gov/pubmed/35204233
http://dx.doi.org/10.3390/antiox11020351