Cargando…

Miconazole Mitigates Acetic Acid-Induced Experimental Colitis in Rats: Insight into Inflammation, Oxidative Stress and Keap1/Nrf-2 Signaling Crosstalk

SIMPLE SUMMARY: The protective effect of miconazole, sulfasalazine (as a reference drug) and their combination on acetic acid (AA)-induced ulcerative colitis (UC) in a rat model was investigated. Pretreatment with miconazole significantly reduced wet colon weight and macroscopic scores, accompanied...

Descripción completa

Detalles Bibliográficos
Autores principales: Alsharif, Ifat A., Fayed, Hany M., Abdel-Rahman, Rehab F., Abd-Elsalam, Reham M., Ogaly, Hanan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869207/
https://www.ncbi.nlm.nih.gov/pubmed/35205169
http://dx.doi.org/10.3390/biology11020303