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Miconazole Mitigates Acetic Acid-Induced Experimental Colitis in Rats: Insight into Inflammation, Oxidative Stress and Keap1/Nrf-2 Signaling Crosstalk
SIMPLE SUMMARY: The protective effect of miconazole, sulfasalazine (as a reference drug) and their combination on acetic acid (AA)-induced ulcerative colitis (UC) in a rat model was investigated. Pretreatment with miconazole significantly reduced wet colon weight and macroscopic scores, accompanied...
Autores principales: | Alsharif, Ifat A., Fayed, Hany M., Abdel-Rahman, Rehab F., Abd-Elsalam, Reham M., Ogaly, Hanan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869207/ https://www.ncbi.nlm.nih.gov/pubmed/35205169 http://dx.doi.org/10.3390/biology11020303 |
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