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Nasal Rifampicin Halts the Progression of Tauopathy by Inhibiting Tau Oligomer Propagation in Alzheimer Brain Extract-Injected Mice

The cell-to-cell transmission of tau aggregates is considered a mechanism underlying the intracerebral spreading of tau pathology in Alzheimer’s disease (AD) and other tauopathies. Recent studies suggest that tau oligomers, rather than fibrils, participate in this process. We previously showed that...

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Detalles Bibliográficos
Autores principales: Umeda, Tomohiro, Uekado, Rumi, Shigemori, Keiko, Eguchi, Hiroshi, Tomiyama, Takami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869211/
https://www.ncbi.nlm.nih.gov/pubmed/35203506
http://dx.doi.org/10.3390/biomedicines10020297