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Repurposing Based Identification of Novel Inhibitors against MmpS5-MmpL5 Efflux Pump of Mycobacterium smegmatis: A Combined In Silico and In Vitro Study

In the current era of a pandemic, infections of COVID-19 and Tuberculosis (TB) enhance the detrimental effects of both diseases in suffering individuals. The resistance mechanisms evolving in Mycobacterium tuberculosis are limiting the efficiency of current therapeutic measures and pressurizing the...

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Detalles Bibliográficos
Autores principales: Shahbaaz, Mohd, Maslov, Dmitry A., Vatlin, Aleksey A., Danilenko, Valery N., Grishina, Maria, Christoffels, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869396/
https://www.ncbi.nlm.nih.gov/pubmed/35203542
http://dx.doi.org/10.3390/biomedicines10020333