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Systemic Administration of the TLR7/8 Agonist Resiquimod (R848) to Mice Is Associated with Transient, In Vivo-Detectable Brain Swelling

SIMPLE SUMMARY: Physiological changes to the body can affect the brain. For example, inflammation that originates in the body can be sensed by the brain. In this study, we used an agent called resiquimod (R848) to stimulate inflammation in the periphery and measured structural and metabolic brain re...

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Detalles Bibliográficos
Autores principales: Zahr, Natalie May, Zhao, Qingyu, Goodcase, Ryan, Pfefferbaum, Adolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869423/
https://www.ncbi.nlm.nih.gov/pubmed/35205140
http://dx.doi.org/10.3390/biology11020274