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Systemic Administration of the TLR7/8 Agonist Resiquimod (R848) to Mice Is Associated with Transient, In Vivo-Detectable Brain Swelling
SIMPLE SUMMARY: Physiological changes to the body can affect the brain. For example, inflammation that originates in the body can be sensed by the brain. In this study, we used an agent called resiquimod (R848) to stimulate inflammation in the periphery and measured structural and metabolic brain re...
Autores principales: | Zahr, Natalie May, Zhao, Qingyu, Goodcase, Ryan, Pfefferbaum, Adolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869423/ https://www.ncbi.nlm.nih.gov/pubmed/35205140 http://dx.doi.org/10.3390/biology11020274 |
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