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Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19

Ubiquitylation and ISGylation are protein post-translational modifications (PTMs) and two of the main events involved in the activation of pattern recognition receptor (PRRs) signals allowing the host defense response to viruses. As with similar viruses, SARS-CoV-2, the virus causing COVID-19, hijac...

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Detalles Bibliográficos
Autores principales: Vere, George, Alam, Md Rashadul, Farrar, Sam, Kealy, Rachel, Kessler, Benedikt M., O’Brien, Darragh P., Pinto-Fernández, Adán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869442/
https://www.ncbi.nlm.nih.gov/pubmed/35204803
http://dx.doi.org/10.3390/biom12020300