Wedelolactone Attenuates N-methyl-N-nitrosourea-Induced Retinal Neurodegeneration through Suppression of the AIM2/CASP11 Pathway

N-methyl-N-nitrosourea (NMU) is widely used to model oxidative stress and inflammation mediated retinal neurodegeneration. Wedelolactone (WD) is known to have antioxidant, anti-inflammatory, and neuroprotective roles. This study tested the therapeutic potential of WD in NMU-induced retinal neurodege...

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Detalles Bibliográficos
Autores principales: Harkin, Kevin, Augustine, Josy, Stitt, Alan W., Xu, Heping, Chen, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869516/
https://www.ncbi.nlm.nih.gov/pubmed/35203520
http://dx.doi.org/10.3390/biomedicines10020311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869516/
https://www.ncbi.nlm.nih.gov/pubmed/35203520
http://dx.doi.org/10.3390/biomedicines10020311

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