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Butyrate Ameliorates Mitochondrial Respiratory Capacity of The Motor-Neuron-like Cell Line NSC34-G93A, a Cellular Model for ALS

Mitochondrial defects in motor neurons are pathological hallmarks of ALS, a neuromuscular disease with no effective treatment. Studies have shown that butyrate, a natural gut-bacteria product, alleviates the disease progression of ALS mice overexpressing a human ALS-associated mutation, hSOD1(G93A)....

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Detalles Bibliográficos
Autores principales: Li, Xuejun, Dong, Li, Li, Ang, Yi, Jianxun, Brotto, Marco, Zhou, Jingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869540/
https://www.ncbi.nlm.nih.gov/pubmed/35204833
http://dx.doi.org/10.3390/biom12020333