The Role of KLF2 in the Regulation of Atherosclerosis Development and Potential Use of KLF2-Targeted Therapy

Kruppel like factor 2 (KLF2) is a mechanosensitive transcription factor participating in the regulation of vascular endothelial cells metabolism. Activating KLF2 in endothelial cells induces eNOS (endothelial nitric oxide synthase) expression, subsequent NO (nitric oxide) release, and vasodilatory e...

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Detalles Bibliográficos
Autores principales: Dabravolski, Siarhei A., Sukhorukov, Vasily N., Kalmykov, Vladislav A., Grechko, Andrey V., Shakhpazyan, Nikolay K., Orekhov, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869605/
https://www.ncbi.nlm.nih.gov/pubmed/35203463
http://dx.doi.org/10.3390/biomedicines10020254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869605/
https://www.ncbi.nlm.nih.gov/pubmed/35203463
http://dx.doi.org/10.3390/biomedicines10020254

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