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Study Designs for Evaluation of Combination Treatment: Focus on Individual Patient Benefit

Combination treatment, i.e., the use of two or more drugs for the same condition, is frequent in medicine if monotherapy yields an insufficient therapeutic response. We review and challenge clinical study designs and formats of reporting outcomes for the evaluation of the benefit/risk ratio of combi...

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Detalles Bibliográficos
Autores principales: Michel, Martin C., Staskin, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869609/
https://www.ncbi.nlm.nih.gov/pubmed/35203479
http://dx.doi.org/10.3390/biomedicines10020270