Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry

Aiming to elucidate the system-wide effects of the alcohol-induced increase in the content of cytochrome P450 2E1 (CYP2E1) on drug metabolism, we explored the array of its protein-protein interactions (interactome) in human liver microsomes (HLM) with chemical crosslinking mass spectrometry (CXMS)....

Descripción completa

Detalles Bibliográficos
Autores principales: Davydov, Dmitri R., Dangi, Bikash, Yue, Guihua, Ahire, Deepak S., Prasad, Bhagwat, Zgoda, Victor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869672/
https://www.ncbi.nlm.nih.gov/pubmed/35204686
http://dx.doi.org/10.3390/biom12020185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869672/
https://www.ncbi.nlm.nih.gov/pubmed/35204686
http://dx.doi.org/10.3390/biom12020185

Ejemplares similares