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Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry
Aiming to elucidate the system-wide effects of the alcohol-induced increase in the content of cytochrome P450 2E1 (CYP2E1) on drug metabolism, we explored the array of its protein-protein interactions (interactome) in human liver microsomes (HLM) with chemical crosslinking mass spectrometry (CXMS)....
Autores principales: | Davydov, Dmitri R., Dangi, Bikash, Yue, Guihua, Ahire, Deepak S., Prasad, Bhagwat, Zgoda, Victor G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869672/ https://www.ncbi.nlm.nih.gov/pubmed/35204686 http://dx.doi.org/10.3390/biom12020185 |
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