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Disinhibition-Like Behavior Correlates with Frontal Cortex Damage in an Animal Model of Chronic Alcohol Consumption and Thiamine Deficiency

Wernicke–Korsakoff syndrome (WKS) is induced by thiamine deficiency (TD) and mainly related to alcohol consumption. Frontal cortex dysfunction has been associated with impulsivity and disinhibition in WKS patients. The pathophysiology involves oxidative stress, excitotoxicity and inflammatory respon...

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Detalles Bibliográficos
Autores principales: Moya, Marta, López-Valencia, Leticia, García-Bueno, Borja, Orio, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869694/
https://www.ncbi.nlm.nih.gov/pubmed/35203470
http://dx.doi.org/10.3390/biomedicines10020260