Lung Fibroblasts from Idiopathic Pulmonary Fibrosis Patients Harbor Short and Unstable Telomeres Leading to Chromosomal Instability

Idiopathic pulmonary fibrosis (IPF) is associated with several hallmarks of aging including telomere shortening, which can result from germline mutations in telomere related genes (TRGs). Here, we assessed the length and stability of telomeres as well as the integrity of chromosomes in primary lung...

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Detalles Bibliográficos
Autores principales: M’Kacher, Radhia, Jaillet, Madeleine, Colicchio, Bruno, Vasarmidi, Eirini, Mailleux, Arnaud, Dieterlen, Alain, Kannengiesser, Caroline, Borie, Claire, Oudrhiri, Noufissa, Junker, Steffen, Voisin, Philippe, Jeandidier, Eric, Carde, Patrice, Fenech, Michael, Bennaceur-Griscelli, Annelise, Crestani, Bruno, Borie, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869717/
https://www.ncbi.nlm.nih.gov/pubmed/35203522
http://dx.doi.org/10.3390/biomedicines10020310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869717/
https://www.ncbi.nlm.nih.gov/pubmed/35203522
http://dx.doi.org/10.3390/biomedicines10020310

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