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Overexpression of bmp4, dazl, nanos3 and sycp2 in Hu Sheep Leydig Cells Using CRISPR/dcas9 System Promoted Male Germ Cell Related Gene Expression

SIMPLE SUMMARY: Male germ cell development plays a crucial role in male reproduction, and gene expression also presents an essential regulatory role in its development. Many studies have been devoted to the induction and differentiation of pluripotent stem cells into germ cells in vitro. However, th...

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Detalles Bibliográficos
Autores principales: Yang, Hua, Deng, Mingtian, Lv, Wenli, Wei, Zongyou, Cai, Yu, Cheng, Peiyong, Wang, Feng, Zhang, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869737/
https://www.ncbi.nlm.nih.gov/pubmed/35205154
http://dx.doi.org/10.3390/biology11020289