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Folate-Targeted Liposomal Formulations Improve Effects of Methotrexate in Murine Collagen-Induced Arthritis

Methotrexate (MTX) is first-line therapy for the treatment of rheumatoid arthritis (RA), however, its use may be limited by side effects notably post-injection malaise. When patients are intolerant or become unresponsive, second-line or antibody therapy may be indicated. A folate-targeted liposomal...

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Detalles Bibliográficos
Autores principales: Guimarães, Diana, Lager, Franck, Renault, Gilles, Guezguez, Jamil, Burnet, Michael, Cunha, Joana, Cavaco-Paulo, Artur, Nogueira, Eugénia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869739/
https://www.ncbi.nlm.nih.gov/pubmed/35203442
http://dx.doi.org/10.3390/biomedicines10020229