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Folate-Targeted Liposomal Formulations Improve Effects of Methotrexate in Murine Collagen-Induced Arthritis
Methotrexate (MTX) is first-line therapy for the treatment of rheumatoid arthritis (RA), however, its use may be limited by side effects notably post-injection malaise. When patients are intolerant or become unresponsive, second-line or antibody therapy may be indicated. A folate-targeted liposomal...
Autores principales: | Guimarães, Diana, Lager, Franck, Renault, Gilles, Guezguez, Jamil, Burnet, Michael, Cunha, Joana, Cavaco-Paulo, Artur, Nogueira, Eugénia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869739/ https://www.ncbi.nlm.nih.gov/pubmed/35203442 http://dx.doi.org/10.3390/biomedicines10020229 |
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