RRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway

Doxorubicin (DOX) is an effective chemotherapeutic agent that plays an unparalleled role in cancer treatment. However, its serious dose-dependent cardiotoxicity, which eventually contributes to irreversible heart failure, has greatly limited the widespread clinical application of DOX. A previous stu...

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Detalles Bibliográficos
Autores principales: Jiao, Yuheng, Li, Yanyan, Zhang, Jiayan, Zhang, Song, Zha, Yafang, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869767/
https://www.ncbi.nlm.nih.gov/pubmed/35204799
http://dx.doi.org/10.3390/biom12020299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869767/
https://www.ncbi.nlm.nih.gov/pubmed/35204799
http://dx.doi.org/10.3390/biom12020299

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