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RRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway

Doxorubicin (DOX) is an effective chemotherapeutic agent that plays an unparalleled role in cancer treatment. However, its serious dose-dependent cardiotoxicity, which eventually contributes to irreversible heart failure, has greatly limited the widespread clinical application of DOX. A previous stu...

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Detalles Bibliográficos
Autores principales:	Jiao, Yuheng, Li, Yanyan, Zhang, Jiayan, Zhang, Song, Zha, Yafang, Wang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869767/ https://www.ncbi.nlm.nih.gov/pubmed/35204799 http://dx.doi.org/10.3390/biom12020299

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