Cargando…

Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model

Malignant melanoma is a type of highly aggressive tumor, which has a strong ability to metastasize to brain, and 60–70% of patients die from the spread of the tumor into the central nervous system. Exosomes are a type of nano-sized vesicle secreted by most living cells, and accumulated studies have...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Peng, Wu, Yunsong, Chen, Wenwen, Zhang, Min, Qin, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869810/
https://www.ncbi.nlm.nih.gov/pubmed/35200349
http://dx.doi.org/10.3390/bios12020089