Cargando…
Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model
Malignant melanoma is a type of highly aggressive tumor, which has a strong ability to metastasize to brain, and 60–70% of patients die from the spread of the tumor into the central nervous system. Exosomes are a type of nano-sized vesicle secreted by most living cells, and accumulated studies have...
Autores principales: | Wang, Peng, Wu, Yunsong, Chen, Wenwen, Zhang, Min, Qin, Jianhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869810/ https://www.ncbi.nlm.nih.gov/pubmed/35200349 http://dx.doi.org/10.3390/bios12020089 |
Ejemplares similares
-
Brain organoid-on-chip system to study the effects of breast cancer derived exosomes on the neurodevelopment of brain
por: Cui, Kangli, et al.
Publicado: (2022) -
Human BBB-on-a-chip reveals barrier disruption, endothelial inflammation, and T cell migration under neuroinflammatory conditions
por: Nair, Arya Lekshmi, et al.
Publicado: (2023) -
Neuroprotective and Neurotoxic Effects of Glial-Derived Exosomes
por: Oyarce, Karina, et al.
Publicado: (2022) -
BBB building
por: Robinson, Richard
Publicado: (2008) -
The Ism between Endothelial Cilia and Endothelial Nanotubules Is an Evolving Concept in the Genesis of the BBB
por: Mentor, Shireen, et al.
Publicado: (2022)