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It Takes More than Two to Tango: Complex, Hierarchal, and Membrane-Modulated Interactions in the Regulation of Receptor Tyrosine Kinases

SIMPLE SUMMARY: Receptor tyrosine kinases probably constitute the most important subfamily of transmembrane receptors with respect to their role in regulating the balance between cell proliferation and cell death. Their activation involves ligand-induced conformational changes followed by their dime...

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Detalles Bibliográficos
Autores principales: Kovacs, Tamas, Zakany, Florina, Nagy, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869822/
https://www.ncbi.nlm.nih.gov/pubmed/35205690
http://dx.doi.org/10.3390/cancers14040944