Tumor Accumulation of PIP-Based KRAS Inhibitor KR12 Evaluated by the Use of a Simple, Versatile Chicken Egg Tumor Model

SIMPLE SUMMARY: One of the goals of nanoplatform-based cancer therapy is to achieve tumor accumulation of anticancer agents. We have focused on PIP-based KRAS inhibitor KR12 (pyrrole–imidazole polyamide indole-seco–CBI conjugate), which has been reported to exhibit tumor growth inhibition in a xenog...

Descripción completa

Detalles Bibliográficos
Autores principales: Higashi, Yuya, Ikeda, Shuji, Matsumoto, Kotaro, Satoh, Shinsuke, Komatsu, Aoi, Sugiyama, Hiroshi, Tamanoi, Fuyuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869854/
https://www.ncbi.nlm.nih.gov/pubmed/35205697
http://dx.doi.org/10.3390/cancers14040951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869854/
https://www.ncbi.nlm.nih.gov/pubmed/35205697
http://dx.doi.org/10.3390/cancers14040951

Ejemplares similares