Cargando…

The PRP19 Ubiquitin Ligase, Standing at the Cross-Roads of mRNA Processing and Genome Stability

SIMPLE SUMMARY: mRNA maturation is absolutely required for proper gene expression and, in recent years, regulators of this process have been found to be tightly intertwined with genome stability. The E3 ubiquitin ligase PRP19 is part of multiple protein complexes that regulate mRNA splicing, RNA:DNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Idrissou, Mouhamed, Maréchal, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869861/
https://www.ncbi.nlm.nih.gov/pubmed/35205626
http://dx.doi.org/10.3390/cancers14040878