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The PRP19 Ubiquitin Ligase, Standing at the Cross-Roads of mRNA Processing and Genome Stability
SIMPLE SUMMARY: mRNA maturation is absolutely required for proper gene expression and, in recent years, regulators of this process have been found to be tightly intertwined with genome stability. The E3 ubiquitin ligase PRP19 is part of multiple protein complexes that regulate mRNA splicing, RNA:DNA...
Autores principales: | Idrissou, Mouhamed, Maréchal, Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869861/ https://www.ncbi.nlm.nih.gov/pubmed/35205626 http://dx.doi.org/10.3390/cancers14040878 |
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