Early Cellular, Molecular, Morphological and Behavioral Changes in the Humanized Amyloid-Beta-Knock-In Mouse Model of Late-Onset Alzheimer’s Disease

The purpose of our study is to investigate early cellular, molecular, morphological and behavioral changes in humanized amyloid-beta-knock-in (hAbKI) mice. Using seven-month-old homozygous hAbKI mice, we studied behavioral phenotype parameters, including spatial learning and memory (Morris Water Maz...

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Detalles Bibliográficos
Autores principales: Kshirsagar, Sudhir, Alvir, Rainier Vladlen, Hindle, Ashly, Kumar, Subodh, Vijayan, Murali, Pradeepkiran, Jangampalli Adi, Reddy, Arubala P., Ramasubramanian, Bhagavathi, Reddy, P. Hemachandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869866/
https://www.ncbi.nlm.nih.gov/pubmed/35203382
http://dx.doi.org/10.3390/cells11040733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869866/
https://www.ncbi.nlm.nih.gov/pubmed/35203382
http://dx.doi.org/10.3390/cells11040733

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