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Impact of β-Amyloids Induced Disruption of Ca(2+) Homeostasis in a Simple Model of Neuronal Activity

Alzheimer’s disease is characterized by a marked dysregulation of intracellular Ca(2+) homeostasis. In particular, toxic β-amyloids (Aβ) perturb the activities of numerous Ca(2+) transporters or channels. Because of the tight coupling between Ca(2+) dynamics and the membrane electrical activity, suc...

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Detalles Bibliográficos
Autores principales: Prista von Bonhorst, Francisco, Gall, David, Dupont, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869902/
https://www.ncbi.nlm.nih.gov/pubmed/35203266
http://dx.doi.org/10.3390/cells11040615