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Impact of β-Amyloids Induced Disruption of Ca(2+) Homeostasis in a Simple Model of Neuronal Activity
Alzheimer’s disease is characterized by a marked dysregulation of intracellular Ca(2+) homeostasis. In particular, toxic β-amyloids (Aβ) perturb the activities of numerous Ca(2+) transporters or channels. Because of the tight coupling between Ca(2+) dynamics and the membrane electrical activity, suc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869902/ https://www.ncbi.nlm.nih.gov/pubmed/35203266 http://dx.doi.org/10.3390/cells11040615 |