ACAGT-007a, an ERK MAPK Signaling Modulator, in Combination with AKT Signaling Inhibition Induces Apoptosis in KRAS Mutant Pancreatic Cancer T3M4 and MIA-Pa-Ca-2 Cells

The mitogen-activated protein kinase (MAPK)/ERK and phosphatidylinositol-3 kinase (PI3K)/AKT pathways are dysregulated in various human cancers, including pancreatic ductal adenocarcinoma (PDAC), which has a very poor prognosis due to its lack of efficient therapies. We have previously identified AC...

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Detalles Bibliográficos
Autores principales: Khandakar, Golam Iftakhar, Satoh, Ryosuke, Takasaki, Teruaki, Fujitani, Kana, Tanabe, Genzoh, Sakai, Kazuko, Nishio, Kazuto, Sugiura, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869916/
https://www.ncbi.nlm.nih.gov/pubmed/35203351
http://dx.doi.org/10.3390/cells11040702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869916/
https://www.ncbi.nlm.nih.gov/pubmed/35203351
http://dx.doi.org/10.3390/cells11040702

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