PARP Inhibitors in Glioma: A Review of Therapeutic Opportunities

SIMPLE SUMMARY: There is a pressing need for new effective treatments against glioma. A promising option is a class of drugs called poly(ADP-Ribose) polymerase (PARP) inhibitors. PARP inhibitors block the repair of DNA damage. They may work synergistically with radiotherapy, chemotherapy and immunot...

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Detalles Bibliográficos
Autores principales: Sim, Hao-Wen, Galanis, Evanthia, Khasraw, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869934/
https://www.ncbi.nlm.nih.gov/pubmed/35205750
http://dx.doi.org/10.3390/cancers14041003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869934/
https://www.ncbi.nlm.nih.gov/pubmed/35205750
http://dx.doi.org/10.3390/cancers14041003

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