The RAF Kinase Inhibitor Protein (RKIP): Good as Tumour Suppressor, Bad for the Heart

The RAF kinase inhibitor protein, RKIP, is a dual inhibitor of the RAF1 kinase and the G protein-coupled receptor kinase 2, GRK2. By inhibition of the RAF1-MAPK (mitogen-activated protein kinase) pathway, RKIP acts as a beneficial tumour suppressor. By inhibition of GRK2, RKIP counteracts GRK2-media...

Descripción completa

Detalles Bibliográficos
Autores principales: Abd Alla, Joshua, Quitterer, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869954/
https://www.ncbi.nlm.nih.gov/pubmed/35203304
http://dx.doi.org/10.3390/cells11040654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869954/
https://www.ncbi.nlm.nih.gov/pubmed/35203304
http://dx.doi.org/10.3390/cells11040654

Ejemplares similares