Traf2 and NCK Interacting Kinase Is a Critical Regulator of Procollagen I Trafficking and Hepatic Fibrogenesis in Mice

Hepatic fibrosis is driven by deposition of matrix proteins following liver injury. Hepatic stellate cells (HSCs) drive fibrogenesis, producing matrix proteins, including procollagen I, which matures into collagen I following secretion. Disrupting intracellular procollagen processing and trafficking...

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Detalles Bibliográficos
Autores principales: Buchl, Samuel C., Hanquier, Zachary, Haak, Andrew J., Thomason, Yvonne M., Huebert, Robert C., Shah, Vijay H., Maiers, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870049/
https://www.ncbi.nlm.nih.gov/pubmed/34677004
http://dx.doi.org/10.1002/hep4.1835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870049/
https://www.ncbi.nlm.nih.gov/pubmed/34677004
http://dx.doi.org/10.1002/hep4.1835

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