Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia

SIMPLE SUMMARY: Patients with cancer suffer from systemic metabolic impairment during cancer progression. An elevated neutrophil–lymphocyte ratio is a negative predictor of outcome. In the present study, we investigate a potential role of neutrophils on host metabolism. We identified widespread neut...

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Detalles Bibliográficos
Autores principales: Petruzzelli, Michele, Ferrer, Miriam, Schuijs, Martijn J., Kleeman, Sam O., Mourikis, Nicholas, Hall, Zoe, Perera, David, Raghunathan, Shwethaa, Vacca, Michele, Gaude, Edoardo, Lukey, Michael J., Jodrell, Duncan I., Frezza, Christian, Wagner, Erwin F., Venkitaraman, Ashok R., Halim, Timotheus Y. F., Janowitz, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870098/
https://www.ncbi.nlm.nih.gov/pubmed/35205709
http://dx.doi.org/10.3390/cancers14040963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870098/
https://www.ncbi.nlm.nih.gov/pubmed/35205709
http://dx.doi.org/10.3390/cancers14040963

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