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Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia
SIMPLE SUMMARY: Patients with cancer suffer from systemic metabolic impairment during cancer progression. An elevated neutrophil–lymphocyte ratio is a negative predictor of outcome. In the present study, we investigate a potential role of neutrophils on host metabolism. We identified widespread neut...
Autores principales: | Petruzzelli, Michele, Ferrer, Miriam, Schuijs, Martijn J., Kleeman, Sam O., Mourikis, Nicholas, Hall, Zoe, Perera, David, Raghunathan, Shwethaa, Vacca, Michele, Gaude, Edoardo, Lukey, Michael J., Jodrell, Duncan I., Frezza, Christian, Wagner, Erwin F., Venkitaraman, Ashok R., Halim, Timotheus Y. F., Janowitz, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870098/ https://www.ncbi.nlm.nih.gov/pubmed/35205709 http://dx.doi.org/10.3390/cancers14040963 |
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