High Throughput Screening Targeting the Dengue NS3-NS5 Interface Identifies Antivirals against Dengue, Zika and West Nile Viruses

Dengue virus (DENV) threatens almost 70% of the world’s population, with no effective therapeutic currently available and controversy surrounding the one approved vaccine. A key factor in dengue viral replication is the interaction between DENV nonstructural proteins (NS) 5 and 3 (NS3) in the infect...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Sundy N. Y., Maher, Belinda, Wang, Chunxiao, Wagstaff, Kylie M., Fraser, Johanna E., Jans, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870125/
https://www.ncbi.nlm.nih.gov/pubmed/35203378
http://dx.doi.org/10.3390/cells11040730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870125/
https://www.ncbi.nlm.nih.gov/pubmed/35203378
http://dx.doi.org/10.3390/cells11040730

Ejemplares similares